The overall goal of the working group is to perform project wide integration of the different data types collected in the separate work packages to determine whether the integration of the diverse data types results in:
- improved understanding of the biology that underlies progression to invasive DCIS;
- improved classifiers to separate indolent from invasive DCIS and
- delivery of improved biomarkers of indolent from invasive DCIS.
To achieve these objectives, three types of analysis will be run: unsupervised analyses, supervised analyses and analyses to identify biomarkers.
Professor Lodewyk Wessels
Group Leader and Head of Division Molecular carcinogenesis
The Netherlands Cancer Institute, Amsterdam, The Netherlands